5-LOX Inhibitor with AprèsFlex®

Category: Extracts

Manufacturer:

Promotes joint, cell & arterial health

  • Made with standardized Boswellia serrata extract
  • Promotes a healthy inflammatory response by inhibiting 5-LOX enzyme
  • Supports joint health, arterial health & healthy cell division

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5-LOX Inhibitor with AprèsFlex®

100 mg, 60 vegetarian capsules

Item Catalog Number: 01639

NON GMO Product

Compounds in Boswellia extract have been shown to bind directly to 5-LOX, an enzyme that transforms fatty acids into inflammatory factors like leukotriene B4. A compound in boswellia called AKBA is the key to this beneficial action. Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia.

AprèsFlex® absorbs 52% more than standard boswellia extract and is standardized for the active AKBA compound.

Benefits at a Glance:

  • Made with standardized Boswellia serrata extract
  • Promotes a healthy inflammatory response by inhibiting 5-LOX enzyme
  • Supports joint health, arterial health & healthy cell division

Better-Absorbed Boswellia

Boswellia is an extract that can inhibit inflammatory factors to support joint and arterial health. In this supplement, we use a standardized form of boswellia called AprèsFlex® that absorbs into the blood 52 percent more than previously available boswellia extracts. Each vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® provides 100 mg of this innovative extract.

5-lipoxygenase (5-LOX) is an enzyme that transforms fatty acids into leukotrienes.1 Since 5-LOX levels increase over time, excess 5-LOX has been linked to some of the common effects of normal aging.2

Boswellia extract inhibits 5-LOX

The Indian plant Boswellia serrata contains compounds shown to inhibit 5-LOX to support joint and arterial health. Boswellia inhibits 5-LOX at the cellular level. Scientific data reveals that a compound in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid) is the key to this beneficial action.3

But boswellia compounds are poorly absorbed into the blood. For this reason, we’ve used AprèsFlex®, a standardized form of boswellia extract. AprèsFlex® absorbs into the blood 52% more than previously available boswellia extracts.4

Dietary factors increase 5-LOX prevalence

The typical American diet adds to 5-LOX levels. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger production of arachidonic acid. The body produces 5-LOX enzyme in response to arachidonic acid.1

Benefits of modulating 5-LOX

5-LOX creates compounds like leukotriene B4 out of arachidonic acid. Inhibiting leukotriene B4 helps support joint, arterial and tissue health.5 Inhibiting 5-LOX also helped support healthy cell division in preclinical models.6

Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.

Supplement facts

Serving Size 1 vegetarian capsule

Amount Per Serving
AprèsFlex® (Boswellia serrata) extract (gum resin) [std. to 20% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) (20 mg)] 100 mg
Other ingredientsmicrocrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.

AprèsFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas – Laila Nutra LLC. U.S. Patent No. 8,551,496 and other patents pending.

Dosage and Use

To inhibit the 5-lipoxygenase enzyme, take one (1) capsule daily, or as recommended by a healthcare practitioner.

Warnings

KEEP OUT OF REACH OF CHILDREN

DO NOT EXCEED RECOMMENDED DOSE

Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

  1. Biochim Biophys Acta - Molecular and Cell Biology of Lipids. 2015;1851(4):331-339.
  2. Faseb j. 2000;14(10):1464-1469.
  3. Clin Pharmacokinet.2011;50(6):349-369.
  4. Mol Cell Biol.2011;354(1):189-197.
  5. Semin Immunol.2017;33:3-15.
  6. Clin Cancer Res.2005;11(5):2089.

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