Melatonin has been shown to help fight cancer, boost immune function, and enable better sleep in some people. This pineal hormone is secreted abundantly in youth but declines with normal aging. 

Melatonin has long been thought of as the “sleep hormone.” It regulates circadian rhythms, the body’s internal biological clock, which can improve sleep patterns. That’s important for optimal health. Inadequate sleep has a well-documented negative impact on immune health, increasing susceptibility to infectious diseases and cancer. But melatonin does much more.

The amino acid derivative N-acetylcysteine protects against a broad array of environmental toxins, helps boost the body’s immune system, and confers other health-promoting benefits.

Your body releases the hormone cortisol in response to stress. Excess cortisol from chronic stress is linked to everything from diabetes to bone loss, weight gain, and sleepless nights. A low-cost supplement called rhodiola combats cortisol’s lethal effects.

Despite their predilection for fatty food, the French have a relatively low risk of dying from heart disease. Wine consumption may explain this “French paradox.” New research reveals that grape plants are loaded with “super-antioxidant” phytocompounds such as quercetin, resveratrol, and others that may benefit human health in myriad ways.

Compelling evidence indicates that the trace mineral boron plays an important role in protecting men against deadly prostate cancer by selectively killing prostate cancer cells while leaving healthy cells unharmed. Adequate boron levels are associated with a 64% reduced risk of prostate cancer as well as a reduction in PSA levels.

Is soy safe? A vocal minority has fueled a “controversy” of misinformation that surrounds this nutritional powerhouse. A review of the published scientific literature uncovers a wealth of studies validating soy’s broad-spectrum benefits, from cardiovascular disease and cancer prevention, to helping to maintain bone density.

A recent review reveals that lycopene shields against environmental and food toxins. Individuals with the highest lycopene concentrations have a 37% lower mortality risk.

Fitness enthusiasts have long prized branched chain amino acids (BCAAs) for their power to boost strength and performance. A newly published study may now give longevity enthusiasts a reason to as well: in an animal model, BCAAs increased life span in part through mitochondrial biogenesis—the spontaneous growth of new mitochondria.

Discovered in Europe, a standardized French Maritime pine extract improves congestive heart failure, reduces markers of metabolic syndrome, and protects against neurological disorders.

Deep vein thrombosis, caused by sitting too long, kills over 100,000 Americans each year. A human study shows that nattokinase and French maritime pine bark improve circulation in the lower legs, lessen leg swelling, and reduce thrombosis (abnormal clot) formation.

Up to 80% of men will suffer from symptoms of prostate enlargement, resulting in frequent urination and possible bladder infections. Studies have shown that a new flower pollen extract can help shrink overgrown prostate tissue and relieve lower urinary tract symptoms.

Scientists have discovered that the endocannabinoid system influences the balance and function of almost all bodily systems. The endocannabinoid system plays an important role in brain function, influencing mood, learning and memory, pain control, sleep, appetite, and more.

With age, the insides of our cells accumulate damaged proteins and other debris that impair youthful function. Humans are equipped with a built-in process that removes these toxic waste products to make room for healthy internal regeneration. This natural, cell housekeeping process is called autophagy.

Using deep-learning artificial intelligence, scientists have identified three plant-based nutrients that can help reverse age-related damage to our existing pool of stem cells.

Low-level inflammation is an underlying factor for six of the ten leading causes of death. Studies have shown that Boswellia extract significantly improved arthritis patients’ pain and function in just seven days while suppressing causative agents involved in chronic inflammation.

Two active forms of vitamin B12 offer support to the aging brain. Preclinical data shows one of the forms protects dopamine levels. People with vitamin B12 deficiencies frequently suffer anemia, weakness, and fatigue. But there are more dangerous effects. Low vitamin B12 levels have been associated with progressive brain atrophy (shrinkage). One study found an astounding 517% greater rate of brain volume loss in people with lower vitamin B12 than those with higher B12 levels.

This protocol is not about reducing the detrimental effects of chronic, excessive alcohol consumption. No nutritional intervention can eliminate the health hazards associated with long-term alcohol overconsumption. Rather, this protocol is intended to provide strategies that may minimize some of the ill effects (ie, hangover) arising from isolated instances of alcohol overindulgence.

Pesticides are absorbed through our air, food, and water. These chemicals can lead to neurodegeneration, cancer, and other disorders. Researchers have found that the flavonoid quercetin offers protection against some of the dangers inflicted by pesticides.

Homocysteine is an amino acid made from a common dietary amino acid, methionine, that inflicts damage to the inner arterial lining (endothelium). Elevated levels of homocysteine have been associated with many diseases, including: cardiovascular disease, congestive heart failure, stroke, migraines, age-related macular degeneration, hearing loss, brain atrophy, Alzheimer disease.

Clinical trials show that vitamin D decreases rates and severity of viral respiratory tract infections. More than 70% of Americans have either deficient or insufficient vitamin D blood levels.

A study showed that lozenges containing zinc acetate are best at curbing a cold and shortening its duration. Zinc lozenges are not meant for everyday use. Common colds are the most common human infection. Based on research published in the 1980s, many people know to start popping zinc lozenges. But not all zinc is the same. Many cold lozenges feature different forms of zinc that are not the most effective choice.

Nootropics are compounds that enhance cognition and facilitate learning. They differ from nutrients that protect against brain aging. Nootropics are for people seeking to improve brain processing speed and mental alertness. Nutrients with nootropic properties have become popular for people of all ages to improve thinking speed and accuracy.

Maintaining balanced hormone levels is essential to overall health. Unfortunately, testosterone levels decline in men as they age. Most men know that testosterone is important for sexual function, but research indicates that it is critical for so much more: maintaining cognitive function and a healthy body weight, improving insulin sensitivity and glucose metabolism, promoting heart health, and more.

Lactoferrin, a protein found in mother’s milk, shows antiviral activity in preclinical trials. It impedes viral binding to cell membranes, while activating immune defenses.

Mention erectile dysfunction and most people think of Viagra® and similar drugs.These drugs work by relaxing the smooth muscles lining the arteries, that increases blood flow to the penis. They also come with some side effects.

B vitamins help guard against cardiovascular disease, neurodegenerative disorders, and vision loss. Because B vitamins are water-soluble and poorly absorbed by aging adults, daily supplementation is often critical.

While medical science is diligently working on the development of an effective treatment, it may be prudent to learn about some protective measures now, and to become informed concerning potential nutritional therapies.

Ashwagandha, an exotic Indian herb, has remarkable stress-relieving properties comparable to those of powerful drugs used to treat depression and anxiety. In addition to its excellent protective effects on the nervous system, ashwagandha may be a promising alternative treatment for a variety of degenerative diseases such as Alzheimer’s and Parkinson’s.

Elevated blood levels of uric acid are present in about 21% of Americans. People frequently associate high uric acid levels with gout, yet many symptom-free individuals have elevated uric acid for years before getting their first gout attack.

Pregnancy can be one of the most joyous times in a woman’s life. But it can also be nerve-racking. There are rules about what to eat (fruit and veggies galore) and what not to eat (no sushi or soft cheeses). Doctors routinely recommend taking prenatal vitamins to ensure the mother and developing fetus are getting the essential nutrients they need. After all, a pregnant woman’s dietary intake is the sole source of nourishment, providing the building blocks for her growing baby. It’s not...

The Life Extension Foundation offers several hundred products. Thinking about the offer of the LEsupplements.com portal I focused on the most advanced ones and these formulas which are dedicated to specific diseases.