Elevated blood levels of uric acid are present in about 21% of Americans. People frequently associate high uric acid levels with gout, yet many symptom-free individuals have elevated uric acid for years before getting their first gout attack.

Life Extension® receives many inquiries about stem cell infusion therapies offered in the United States and other countries. Our current view from small human trials is that there may be a benefit to infusions of exosomes that are naturally secreted from healthy stem cells. Stem cell exosomes have regenerative properties that help restore functional cells needed to maintain tissue and organ viability. Overlooked when considering exosome treatments is the ability to rejuvenate existing stem...

For thousands of years, turmeric root has been used as a traditional Indian medicine. The turmeric spice, which gives curry its golden color, has been recognized for wide-ranging health benefits.1-5 The most beneficial compounds in turmeric are curcuminoids, which include curcumin and related compounds. One animal study showed lifespan extension up to 26% with curcumin supplementation.6 

As we age, our cognitive abilities decline. But it doesn’t have to be this way. Scientists have identified specific nutrients that protect the aging brain.1-10 One of these is a sage extract that has demonstrated remarkable cognitive-enhancing activities.11 In clinical studies, this sage extract increased memory performance in older adults by nearly 60%.

Pregnancy can be one of the most joyous times in a woman’s life. But it can also be nerve-racking. There are rules about what to eat (fruit and veggies galore) and what not to eat (no sushi or soft cheeses). Doctors routinely recommend taking prenatal vitamins to ensure the mother and developing fetus are getting the essential nutrients they need. After all, a pregnant woman’s dietary intake is the sole source of nourishment, providing the building blocks for her growing baby. It’s not...

In year 2001, Life Extension® researchers actively sought a method to boost levels of a coenzyme in aging people. We knew this was critical to achieving healthy longevity. Consumers had to wait until 2014 for a validated method to become available. This coenzyme is called NAD+ and is vital for energizing cells and supporting youthful cellular processes.

The liver is a primary defense against daily toxins. People used to think that the main threat to their liver was alcohol. Today's nemesis is obesity. The result is an epidemic crisis of non-alcoholic fatty liver disease (NAFLD). Liver-related deaths jumped 65% between 1999 and 2016. Milk thistle extract has demonstrated benefits for non-alcoholic fatty liver disease, alcoholic liver disease, and cirrhosis. When standardized extracts of milk thistle are combined with a phospholipid...

Burnout is real. In May 2019, the World Health Organization officially included it in its International Classification of Diseases. This recognition confirmed that burnout was not a figment of the imagination, or something suffered only by “weak” or “unmotivated” people.1 Medical treatments are limited. The Mayo Clinic recommends sleep and relaxation.2 But now there’s hope for the 30% to 72% of working people who suffer from burnout syndrome.3,4

Although aging impacts the whole body, the most visible effects occur in our skin, hair, and nails. As we mature, our outer tissues lose their framework of structural proteins, namely keratin, collagen, and elastin. Loss of structural proteins in the body is further compounded by external factors such as pollution and sun exposure. To counter this visible deterioration, scientists have investigated nutrients that can be taken orally to rebuild the underlying architecture of the skin, hair,...

Even if you are not doing a deep dive into detoxification protocols, there is a vast array of clinical settings in which glutathione may impact health conditions

Menopausal women can obtain symptomatic relief with proper use of estrogen, progesterone, and other hormones. Life Extension® has long advocated for bio-identical hormones as opposed to horse urine-derived estrogens and synthetic progestogens. Some women, however, choose not to replace hormones and endure years of misery. A non-hormonal approach has been demonstrated with an extract made from Siberian rhubarb. It's been used successfully in Germany since 1993.

A new vision-robbing culprit has emerged that is more prevalent than sunlight exposure. Our round-the-clock use of smartphones and computers exposes our eyes to an unnaturally high amount of blue light. Research shows that blue light is damaging to the retina and other parts of our eye.1

An estimated 20 million Americans or more suffer from dry eye syndrome. This condition occurs when the eyes don’t produce enough quality tears. It’s one of the most common eye conditions seen by physicians.1 Dry eye symptoms include burning, stinging, grittiness, tearing, foreign body sensation, ocular fatigue, and dryness. Dry eye syndrome significantly affects quality of life.1,2

Anxiety and mood disorders are now being recognized as major medical and societal issues. With millions of people medicated for mood disorders that include anxiety and mild depression, researchers have sought a safer way to reduce their impact. In a unique discovery, two specific probiotic organisms have been identified that show impressive reductions in the manifestation of stress, anxiety, and depression. Human studies on two unique probiotics (Lactobacillus helveticus R0052 and...

Recent studies have expanded our understanding of vitamin K. We've long known it to be essential for bone density along with heart health.1-3 One study found that people aged 55 and older with the highest intake of vitamin K had a 57% lower rate of death from coronary heart disease over 10 years—and a 26% lower rate of death from any cause.4 A 2017 study showed that people with the highest intake of vitamin K had a 22% lower rate of bone fractures.5

New research indicates that melatonin does much more than help some people sleep better. Exciting studies show that melatonin’s multifaceted effects may improve treatment outcomes in cancer patients and extend their lives. Additional applications of melatonin include guarding the nervous system against degenerative diseases—such as Alzheimer’s disease and stroke—and preventing debilitating migraines.

Vitamin C’s health-boosting benefits go far beyond fighting the common cold and flu. In fact, nutritional scientists have discovered that this potent antioxidant is crucial in supporting the health of the cardiovascular system, kidneys, bones, respiratory system, and more.

The Life Extension Foundation offers several hundred products. Thinking about the offer of the LEsupplements.com portal I focused on the most advanced ones and these formulas which are dedicated to specific diseases.

An inevitable consequence of aging is a rapid decline in our cellular energy levels. The outward effects often manifest as a sense of overall fatigue, depression, and sexual dysfunction. The internal effect of a cellular energy deficit is a greater vulnerability to a host of degenerative diseases.

Quercetin is naturally abundant in plant foods and as a result is highly bioavailable.Nonetheless, most people do not obtain sufficient quercetin levels through their daily diets. This is unfortunate because large-scale epidemiological studies show that sustained high intake of quercetin and related flavonoids provides substantial protection against cardiovascular disease.

Zinc is required by the body for more than 2,000 transcription factors involved in gene expressions of various proteins.1 What this means in everyday language is that thousands of essential biological functions are dependent on zinc.

Women who properly replace their estrogen and progesterone usually feel better, sleep better, look better, think better, have stronger bones, firmer muscles, improved endothelial function, and longer life spans.